| OBJECTIVE: To study the clinical efficacy of unilateral puncture treatment of OCVF with manipulation and osteoplasty combined with bone-filled mesh bag PKP. Methods: A total of 110 patients with OVCF admitted to Hubei Combined Hospital of Traditional Chinese and Western Medicine in the last 5 years up to February 2024 were selected, and 60 patients were finally included in this study after selection; the study group used unilateral puncture of manipulative revision combined with bone-filling mesh bag PKP, and the observation group used bilateral puncture with bone mesh bag, with 30 cases in each of the two groups. Functional evaluation, imaging evaluation, bone cement dosage, bone cement distribution and postoperative complications before and after surgery and at the last follow-up were observed and compared between the two groups and statistically analysed. Results: Comparing the ODI and VAS scores of the two groups of patients before and after surgery, the ODI and VAS scores were significantly lower in the 3d postoperative period compared with the preoperative period, and the difference between before and after the surgery was statistically significant (P＜0.05); the two scores continued to decrease in the final follow-up compared with the 3d postoperative period, and the difference was statistically significant (P＜0.05), and the difference in the scores was not statistically significant (P＞0.05) when comparing the data between the two groups. The difference between the two groups was not statistically significant (P>0.05), and there was no significant difference in the clinical efficacy of the surgical methods between the two groups. The height of the vertebral body was significantly restored before and after surgery, and the cobb angle of the posterior convexity of the injured vertebrae was significantly reduced, with statistically significant differences (P < 0.05). 0.05); at the last follow-up, the observation group was better than the study group in both indicators, and the difference was statistically significant (P < 0.05). The operation time of the study group was significantly lower than that of the control group, and the amount of bone cement used in the study group was significantly less than that of the control group, with a statistically significant difference (P < 0.05). Comparing the distribution of bone cement between the two groups, the difference was not statistically significant (P > 0.05). The bone cement leakage rate of the unilateral mesh bag group was significantly smaller than that of the bilateral group, and the difference between the two groups was statistically significant (P < 0.05). There was no statistically significant difference in the postoperative occurrence of adjacent vertebral body re-fracture, hospitalisation cost and length of hospitalisation between the two groups. Conclusion: Manipulative restoration combined with bone-filled mesh bag unilateral PKP and mesh bag PKP bilateral puncture treatment for osteoporotic thoracolumbar vertebral fracture in the elderly can achieve satisfactory efficacy, and the former has the advantages of reducing the rate of bone cement leakage and shortening the operation time. |