文章摘要
基于“骨肉不相亲理论”探讨退行性腰椎管狭窄症与椎旁肌退变的相关性
Correlation between degenerative lumbar spinal stenosis and paravertebral muscle degeneration based on the theory of "bone and flesh not close"
DOI:
中文关键词: 腰椎管狭窄症  椎旁肌  脂肪浸润  骨肉不相亲
英文关键词: Lumbar spinal stenosis  paravertebral muscle  fat infiltration  incompatibility of bone and flesh
基金项目:新疆维吾尔自治区天山英才项目(TSYC202301B041);新疆维吾尔自治区科技创新领军人才-高层次领军人才项目(2022TSYCLJ0027) 通讯作者:黄异飞,主任医师,博士研究生导师,主要从事脊柱相关疾病的研究,E-mail:jerkhuang@163.com
作者单位邮编
汪海龙* 新疆医科大学第四临床医学院 830099
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中文摘要:
      目的 基于“骨肉不相亲理论”探讨退行性腰椎管狭窄症与椎旁肌退变的相关性。方法? 回顾性分析2023年1月至2024年1月我院收治腰椎管狭窄症患者根据纳入排除标准120例,均行腰椎MRI检查,从而获取腰椎 L4/L5段T2加权像轴位图像,通过测量椎旁肌总肌肉横截面积 (Total Muscle Cross-Sectinal Area,TMCSA)、椎体终板面积(Vertebral endplate,VBE)、功能肌肉面积(Functional Muscle Cross-Sectinal Area,FMCSA)、脂肪浸润面积 (Fat Infiltration Cross-Sectional Area,FCSA)、相对横截面积 (Relative crosssectional area,RCSA)、脂肪浸润程度(Dixon-based Fat Fraction,DFF)的数值 ,并记录患者的疼痛视觉模拟评分(VAS)、Oswestry功能障碍指数(ODI)以及采用Schizas分级系统对腰椎椎管狭窄的程度进行分级。通过分析相关测量数据,对椎旁肌总肌肉横截面积 (TMCSA)、功能肌肉面积(FMCSA)、脂肪浸润面积 (FCSA)、相对横截面积 (RCSA)、脂肪浸润程度(DFF)与腰椎椎管狭窄程度的Schizas分级进行相关性分析。结果? Schizas分级所反映的腰椎管狭窄严重程度与椎旁肌的FMCSA、FCSA及DFF之间均存在显著相关性(P<0.001),其中FMCSA与狭窄程度呈负相关。结论 椎旁肌肉脂肪浸润与腰椎椎管狭窄程度密切相关,椎旁肌的功能肌肉面积、脂肪浸润面积、相对横截面积、脂肪浸润程度与腰椎管狭窄程度以及疼痛视觉模拟评分(VAS)、Oswestry功能障碍指数(ODI)呈较强的相关性。
英文摘要:
      Objective To investigate the correlation between degenerative lumbar spinal stenosis and paravertebral muscle degeneration based on the "Bone-Flesh Unintimacy Theory". Methods A retrospective analysis was conducted on 120 patients with lumbar spinal stenosis admitted to our hospital from January 2023 to January 2024. All patients underwent lumbar MRI examinations to obtain axial T2-weighted images of the L4/L5 segment. The study measured the following parameters: Total Muscle Cross-Sectional Area (TMCSA), Vertebral Endplate Area (VBE), Functional Muscle Cross-Sectional Area (FMCSA), Fat Infiltration Cross-Sectional Area (FCSA), Relative Cross-Sectional Area (RCSA), and Dixon-based Fat Fraction (DFF). The degree of lumbar spinal stenosis was classified using the Schizas grading system. Through analysis of relevant measurement data, we conducted correlation analysis between the total muscle cross-sectional area (TMCSA), functional muscle area (FMCSA), fat infiltration area (FCSA), relative cross-sectional area (RCSA), and fat infiltration degree (DFF) of paravertebral muscles with the Schizas classification of lumbar spinal stenosis severity. Results showed significant correlations (P<0.001) between the severity of lumbar spinal stenosis reflected by the Schizas classification and the FMCSA, FCSA, and DFF of paravertebral muscles, with FMCSA showing a negative correlation to stenosis severity. Conclusion Paravertebral muscle fat infiltration is closely related to the severity of lumbar spinal stenosis, and the functional muscle area, fat infiltration area, relative cross-sectional area, and fat infiltration degree of paravertebral muscles exhibit strong correlations with the degree of lumbar spinal stenosis.
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