基于“温之以气,补之以味”理论探讨许红英主任论治卵巢低反应经验 |
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中文关键词: “温之以气,补之以味” 卵巢低反应 辅助生殖技术 |
英文关键词: "Warming with Qi, Tonifying with Flavor" Poor Ovarian Response Assisted Reproductive Technology |
基金项目:湖北省中医药管理局中医药科研项目(ZY2025L061);荆州市科技计划项目(2024HD171);荆州市中医医院2024年度中医药研究所自主选题项目(ZZXT2024Y09) |
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中文摘要: |
卵巢低反应(Poor Ovarian Response, POR)是辅助生殖技术中常见的临床难题,表现为卵巢对促性腺激素刺激反应低下,卵泡发育迟缓或数量减少,最终导致获卵数减少和妊娠率下降。中医学将POR归属于“月经过少”“不孕”等范畴,许红英主任宗《素问·阴阳应象大论》“形不足者,温之以气;精不足者,补之以味”之旨,认为POR之病机属肾阳气虚、肾精亏虚。因而在治疗方面,强调气温与味补兼施,共奏改善卵巢反应性之效。本文基于上述理论,旨在系统阐述POR的病因病机及中医治则,为临床诊疗提供理论参考与借鉴。 |
英文摘要: |
Poor Ovarian Response (POR) is a common clinical challenge in assisted reproductive technology, characterized by diminished ovarian response to gonadotropin stimulation, delayed follicular development, and reduced follicle count, ultimately leading to fewer retrieved oocytes and lower pregnancy rates. In traditional Chinese medicine (TCM), POR is categorized under conditions such as “scanty menstruation” and “infertility”. Professor Xu Hongying, guided by the principle from Su Wen·Yin Yang Ying Xiang Da Lun that “those with insufficient form should be warmed with qi, and those with deficient essence should be supplemented with flavor”, proposes that the pathogenesis of POR involves both deficiency of kidney-yang qi and deficiency of kidney essence. Accordingly, the treatment emphasizes simultaneous warming and supplementation—specifically, warming kidney-yang and replenishing kidney essence—to dynamically regulate kidney yin-yang and essence-qi, thereby synergistically improving ovarian responsiveness. Based on this theory, this paper aims to systematically elaborate on the etiology, pathogenesis, and TCM treatment principles of POR, providing theoretical reference and guidance for clinical practice. |
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